IMMUNOTHERAPY INNOVATIONS IN CANCER TREATMENT: A NEW ERA OF ONCOLOGY

Authors

  • Dr. Ayesha Khan Department of Oncology, University of the Punjab, Lahore, Pakistan. Author
  • Dr. Omar Malik National Institute of Health, Islamabad, Pakistan. Author
  • Prof. Emily Carter Department of Hematology–Oncology, Johns Hopkins University, Baltimore, USA. Author
  • Prof. David Nguyen Department of Molecular Oncology, University College London, UK. Author

DOI:

https://doi.org/10.71465/jhmri63

Keywords:

immunotherapy, checkpoint inhibitors, CAR-T cell, RNA vaccine, oncolytic virus, delivery systems

Abstract

Cancer immunotherapy has heralded a transformative shift in oncology, leveraging the immune system to achieve durable responses across diverse malignancies. Recent innovations—ranging from checkpoint blockade and CAR-T cell therapies to personalized RNA vaccines, oncolytic viruses, and novel delivery platforms—are extending therapeutic reach into solid tumors and refractory disease. This review synthesizes cutting-edge developments from 2024–2025, emphasizing mechanistic insights, clinical trial outcomes, and delivery innovations. Key challenges—immune evasion, resistance, toxicity, and logistical constraints—are addressed alongside emerging solutions like nanocarriers, biomaterials, and computational multi-omics. This synthesis highlights a new era in immuno-oncology that bridges bench and bedside.

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Published

2023-09-30

Issue

Vol. 1 No. 3 (2023): Journal of Health, Medical Research and Innovations

Section

Articles

License

Copyright (c) 2023 Dr. Ayesha Khan, Dr. Omar Malik, Prof. Emily Carter, Prof. David Nguyen (Author)

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

All articles published in the Journal of Health, Medical Research and Innovations are distributed under an open access license. Authors retain copyright and grant the journal the right of first publication. The published content can be freely accessed, shared, and reused for non-commercial purposes, provided proper citation is maintained and the original work is not altered.